PRA rcd1 Rod Cone DysplasiaDog

64,90

Specific to the Irish Setter

Tests turnaround : 3-6 days or Express 3 days
Breeds : Setter Irlandais Rouge, Setter Irlandais Rouge Et Blanc
Samples : Buccal swab, or Blood in EDTA tube, or Blood in dry tube

Clear
SKU: pra-rcd1-rod-cone-dysplasia-dog Category:
N/N : Normal, no copies of the PRA rcd1 mutation. N/PRA rcd1 : Normal, one copy of the PRA rcd1 mutation. PRA rcd1/PRA rcd1 : 2 copies of the PRA rcd1 mutation, the dog may develop this disease.

What is the PRA rcd1 rod-cone dysplasia ?

The PRA rcd1 is an incurable disease. The degeneration of the photo-receptors of the eye begins at the age of 2 weeks and becomes complete after one year. The dog is then completely blind.

Type of sample

Here is the list of the different types of samples that are accepted for this test :
  • Buccal swab
  • Blood in EDTA tube
  • Blood in dry tube

Available breeds for the test : PRA rcd1 Rod Cone Dysplasia - Dog


The following breeds are recognized :
  • Setter Irlandais Rouge
  • Setter Irlandais Rouge Et Blanc

Understanding results of the test : PRA rcd1 Rod Cone Dysplasia - Dog


N/N : Normal, no copies of the PRA rcd1 mutation. N/PRA rcd1 : Normal, one copy of the PRA rcd1 mutation. PRA rcd1/PRA rcd1 : 2 copies of the PRA rcd1 mutation, the dog may develop this disease.
Test name : PRA rcd1 Rod Cone Dysplasia - Dog
Gene Mutation : PDE6B c.2420G>A
Heredity : autosomal recessive (more information)
Test resultPRA rcd1 Rod Cone Dysplasia - Dog status (PDE6B c.2420G>A)Health status
N/NNo copy of the PRA rcd1 mutationAnimal is normal (clear)
N/PRA rcd11 copy of the PRA rcd1 mutationAnimal is normal (clear)
PRA rcd1/PRA rcd12 copies of the PRA rcd1 mutationAnimal is, will or could be affected

Cross table of the test : PRA rcd1 Rod Cone Dysplasia - Dog


Mother N/NMother N/PRA rcd1Mother PRA rcd1/PRA rcd1
Father N/N100% N/N50% N/N
50% N/PRA rcd1
100% N/PRA rcd1
Father N/PRA rcd150% N/N
50% N/PRA rcd1
25% N/N
50% N/PRA rcd1
25% PRA rcd1/PRA rcd1
50% N/PRA rcd1
50% PRA rcd1/PRA rcd1
Father PRA rcd1/PRA rcd1100% N/PRA rcd150% N/PRA rcd1
50% PRA rcd1/PRA rcd1
100% PRA rcd1/PRA rcd1

Certificate example for the test : PRA rcd1 Rod Cone Dysplasia - Dog

Click on the example certificate below to open it.

certificate

References

Suber, M L et al. “Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phosphodiesterase beta-subunit geneProceedings of the National Academy of Sciences of the United States of America vol. 90,9 (1993): 3968-72.

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