TNS Trapped Neutrophil Syndrome

64, 90

Specific to the Border Collie

Tests turnaround : 3-6 dage eller Express 3 dage
Racer : Border Collie
Prøver : Buccal vatpind eller blod i EDTA tube eller blod i tørrør

Klart
Sku: tns-trapped-neutrophil-syndrome-border-collie Kategori:
N/N : Normal, no copies of the TNS mutation. N/TNS : Normal, one copy of the TNS mutation. TNS/TNS : 2 copies of the TNS mutation, the dog may develop this disease.

What is the TNS Trapped Neutrophil Syndrome ?

The TNS is a disease of the immune system that is specific to the Border Collie. The neutrophils are correctly produced and mature properly however they are not released into the bloodstream. Thus, the immune system is less effective. The first symptoms can be observed in puppies as early as 2 weeks old and they are usually euthanized before the age of 1 month. The symptoms included loss of appetite, diarrhea and a poor mobility.

Type prøve

Her er en liste over de forskellige typer af prøver, der er accepteret til denne test:
  • Buccale vatpind
  • Blod i EDTA tube
  • Blod i tørre tube

Tilgængelig race for testen: TNS Trapped Neutrophil Syndrome


Følgende race er anerkendt:
  • Border Collie

Forståelse af resultaterne af testen: TNS Trapped Neutrophil Syndrome


N/N : Normal, no copies of the TNS mutation. N/TNS : Normal, one copy of the TNS mutation. TNS/TNS : 2 copies of the TNS mutation, the dog may develop this disease.
Test navn: TNS Trapped Neutrophil Syndrome
Genmutation: VPS13B g.4411956_4411960delGTTT
Arvelighed: autosomal recessiv (mere information)
Test resultatTNS Trapped Neutrophil Syndrome statusVPS13B g.4411956_4411960delGTTT)Sundhedsstatus
N/NNo copy of the TNS mutationDyret er normalt (klart)
N/TNS1 copy of the TNS mutationDyret er normalt (klart)
TNS/TNS2 copies of the TNS mutationDyr er, vil eller kan blive påvirket

Kryds tabel over testen: TNS Trapped Neutrophil Syndrome


Mor N/NMor N/TNSMor TNS/TNS
Far N/N100% N/N50% N/N
50% N/TNS
100% N/TNS
Far N/TNS50% N/N
50% N/TNS
25% N/N
50% N/TNS
25% TNS/TNS
50% N/TNS
50% TNS/TNS
Far TNS/TNS100% N/TNS50% N/TNS
50% TNS/TNS
100% TNS/TNS

Eksempel på certifikat for testen: TNS Trapped Neutrophil Syndrome

Klik på eksempel certifikatet nedenfor for at åbne det.

Certifikat

Referencer

Mizukami K, Shoubudani T, Nishimoto S, Kawamura R, Yabuki A, Yamato O. Trapped neutrophil syndrome in a Border Collie dog: clinical, clinico-pathologic, and molecular findings. J Vet Med Sci. 2012 Jun;74(6):797-800. Epub 2012 Jan 12.

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