MPS VII Mucopolysaccharidosis type VII – Cat

44,90 

Tests turnaround : 3-6 days or Express 3 days
Breeds : Many breeds, see product description
Samples : Buccal swab, or Blood in EDTA tube, or Blood in dry tube

Clear
SKU: mps-vii-mucopolysaccharidosis-type-vii-cat Category:
N/N : Normal, no copy of the MPS VII mutation. N/MPS VII : Normal, one copy of the MPS VII mutation. MPS VII/MPS VII : 2 copies of the MPS VII mutation, the cat may develop this disease.

What is Mucopolysaccharidosis type VII – MPS VII ?

The Mucopolysaccharidosis type VII (MSPVII) causes skeletal and ocular abnormalities. These symptoms are due to a disorder in lysosomal storage.

Type of sample

Here is the list of the different types of samples that are accepted for this test :
  • Buccal swab
  • Blood in EDTA tube
  • Blood in dry tube

Available breeds for the test : MPS VII Mucopolysaccharidosis type VII - Cat


The following breeds are recognized :
  • Abyssin
  • American Curl
  • American Shorthair
  • American Wirehair
  • Angora Turc
  • Asian
  • Autre Race
  • Balinais
  • Bengal
  • Bleu Russe
  • Bobtail Americain
  • Bobtail Des Kouriles
  • Bobtail Japonais
  • Bombay
  • British Longhair
  • British Shorthair
  • Burmese Americain
  • Burmese Anglais
  • Burmilla
  • Californian Rex
  • Californian Spangled
  • Ceylan
  • Chartreux
  • Chausie
  • Cornish Rex
  • Cymric
  • Devon Rex
  • Donskoy
  • Europeen
  • Exotic Shorthair
  • German Rex
  • Havana Brown
  • Highland Fold
  • Highland Straight
  • 35 other breeds are available. Display all these breeds.

Understanding results of the test : MPS VII Mucopolysaccharidosis type VII - Cat


N/N : Normal, no copy of the MPS VII mutation. N/MPS VII : Normal, one copy of the MPS VII mutation. MPS VII/MPS VII : 2 copies of the MPS VII mutation, the cat may develop this disease.
Test name : MPS VII Mucopolysaccharidosis type VII - Cat
Gene Mutation : GUSB c.1421T>G and c.1424C>T
Heredity : autosomal recessive (more information)
Penetrance : complete (more information)
Test resultMPS VII Mucopolysaccharidosis type VII - Cat status (GUSB c.1421T>G and c.1424C>T)Health status
N/NNo copy of the MPS VII mutationAnimal is normal (clear)
N/MPS VII1 copy of the MPS VII mutationAnimal is normal (clear)
MPS VII/MPS VII2 copies of the MPS VII mutationAnimal is, will or could be affected

Cross table of the test : MPS VII Mucopolysaccharidosis type VII - Cat


Mother N/NMother N/MPS VIIMother MPS VII/MPS VII
Father N/N100% N/N50% N/N
50% N/MPS VII
100% N/MPS VII
Father N/MPS VII50% N/N
50% N/MPS VII
25% N/N
50% N/MPS VII
25% MPS VII/MPS VII
50% N/MPS VII
50% MPS VII/MPS VII
Father MPS VII/MPS VII100% N/MPS VII50% N/MPS VII
50% MPS VII/MPS VII
100% MPS VII/MPS VII

Certificate example for the test : MPS VII Mucopolysaccharidosis type VII - Cat

Click on the example certificate below to open it.

certificate

References

Wang, P., Sorenson, J., Strickland, S., Mingus, C., Haskins, M.E., and Giger, U. (2015). Mucopolysaccharidosis VII in a Cat Caused by 2 Adjacent Missense Mutations in the GUSB Gene. J. Vet. Intern. Med. 29, 1022–1028.

Fyfe, J.C., Kurzhals, R.L., Lassaline, M.E., Henthorn, P.S., Alur, P.R., Wang, P., Wolfe, J.H., Giger, U., Haskins, M.E., Patterson, D.F., et al. (1999). Molecular basis of feline beta-glucuronidase deficiency: an animal model of mucopolysaccharidosis VII. Genomics 58, 121–128.

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