What is the HC Hereditary Cataract ?
The HC genetic disease affects about 8% of dogs in terrier breeds. This genetic disease was discovered in the late 1970s. The first signs of hereditary cataracts appear from a few weeks to a few months then the dog becomes completely blind after one or two years.
Available breeds no ka hoao ana: HC Hereditary Cataract o Terrier
ʻO kēia breeds i ike:
- American Staffordshire Terrier
- Autre Race
- Bouledogue Français
- Staffordshire Bull Terrier
- Terrier De Boston
Hoʻomaopopo i nā hualoaʻa o ka hoʻokolohua. HC Hereditary Cataract o Terrier
'Ōewe Mutation: HSF4 g.85286582_insC
nā kūpuna mai: autosomal recessive (hou 'ike)
|hoʻokolohua hopena||HC Hereditary Cataract o Terrier kūlana (HSF4 g.85286582_insC)||Health you|
|N/N||No copy of the HC mutation||Animal mea maʻamau (moakaka)|
|N/HC||1 copy of the HC mutation||Animal mea maʻamau (moakaka)|
|HC/HC||2 copies of the HC mutation||Animal mea, e 'ole hiki ke loli|
Keʻa papa o ka hoʻokolohua. HC Hereditary Cataract o Terrier
|Makuahine N/N||Makuahine N/HC||Makuahine HC/HC|
|Makuakāne N/N||100% N/N||50% N/N|
|Makuakāne N/HC||50% N/N|
|Makuakāne HC/HC||100% N/HC||50% N/HC|
Palapala laʻana no ka hoao ana: HC Hereditary Cataract o Terrier
E kaomi ma luna o ka hana palapala ma lalo nei, e wehe ia.
E hoʻomaopopo '
Mellersh CS, Pettitt L, Forman OP, Vaudin M, Barnett KC. 2006. Identification of mutations in HSF4 in dogs of three different breeds with hereditary cataracts. Vet Ophthalmol. 9:369-378.
Mellersh CS, Graves KT, McLaughlin B, Ennis RB, Pettitt L, Vaudin M, Barnett KC. Mutation in HSF4 associated with early but not late-onset hereditary cataract in the Boston terrier. Journal of Heredity 2007; 98(5):531-533