SDCA1 Spongy cerebellar degeneration with cerebellar ataxia

64,90

परीक्षण बदलाव : 3-6 days or Express 3 days
Breeds : Many breeds, see product description
नमूने : Buccal swab, or Blood in EDTA tube, or Blood in dry tube

स्पष्ट
Sku: sdca1-spongy-cerebellar-degeneration-with-cerebellar-ataxia श्रेणी:
N/N : Normal, no copies of the SDCA1 mutation. N/SDCA1 : Normal, one copy of the SDCA1 mutation. SDCA1/SDCA1 : 2 copies of the SDCA1 mutation, the dog may develop this disease.

The symptoms of SDCA1 Spongy cerebellar degeneration with cerebellar ataxia

The SDCA1 is a neurodegenerative disease that mainly affects Dutch shepherds. The first signs of the disease appear between the age of 4-8 weeks. The symptoms are movement disorders, loss of stability and difficulty coordinating movements of their legs. Generally, the dogs affected by SDCA1 are euthanizing.

Another disease named SDCA2 with similar symptoms in the Belgian and Dutch Shepherds dogs exists.

नमूना का प्रकार

यहां विभिन्न प्रकार के नमूनों की सूची दी गई है जो इस परीक्षण के लिए स्वीकार किए जाते हैं:
  • Buccal swab
  • Blood in EDTA tube
  • Blood in dry tube

Available breeds for the test : SDCA1 Spongy cerebellar degeneration with cerebellar ataxia


The following breeds are recognized :
  • Autre Race
  • Berger Belge
  • Berger Belge Groenendael
  • Berger Belge Laekenois
  • Berger Belge Malinois
  • Berger Belge Tervueren
  • Berger Hollandais A Poil Court
  • Berger Hollandais A Poil Dur
  • Berger Hollandais A Poil Long
  • Inconnue

Understanding results of the test : SDCA1 Spongy cerebellar degeneration with cerebellar ataxia


N/N : Normal, no copies of the SDCA1 mutation. N/SDCA1 : Normal, one copy of the SDCA1 mutation. SDCA1/SDCA1 : 2 copies of the SDCA1 mutation, the dog may develop this disease.
Test name : SDCA1 Spongy cerebellar degeneration with cerebellar ataxia
Gene Mutation : KCNJ10 c.986T>C
Heredity : autosomal recessive (more information)
Test resultSDCA1 Spongy cerebellar degeneration with cerebellar ataxia status (KCNJ10 c.986T>C)Health status
N/NNo copy of the SDCA1 mutationAnimal is normal (clear)
N/SDCA11 copy of the SDCA1 mutationAnimal is normal (clear)
SDCA1/SDCA12 copies of the SDCA1 mutationAnimal is, will or could be affected

Cross table of the test : SDCA1 Spongy cerebellar degeneration with cerebellar ataxia


Mother N/NMother N/SDCA1Mother SDCA1/SDCA1
Father N/N100% N/N50% N/N
50% N/SDCA1
100% N/SDCA1
Father N/SDCA150% N/N
50% N/SDCA1
25% N/N
50% N/SDCA1
25% SDCA1/SDCA1
50% N/SDCA1
50% SDCA1/SDCA1
Father SDCA1/SDCA1100% N/SDCA150% N/SDCA1
50% SDCA1/SDCA1
100% SDCA1/SDCA1

परीक्षण के लिए प्रमाण पत्र उदाहरण: SDCA1 Spongy cerebellar degeneration with cerebellar ataxia

इसे खोलने के लिए नीचे दिए गए उदाहरण प्रमाण पत्र पर क्लिक करें।

प्रमाणपत्र

References

Mauri, Nico et al. “A Missense Variant in KCNJ10 in Belgian Shepherd Dogs Affected by Spongy Degeneration with Cerebellar Ataxia (SDCA1)” G3 (Bethesda, Md.) vol. 7,2 663-669. 21 Dec. 2016, doi:10.1534/g3.116.038455

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.