DEB Dystrophic Epidermolysis BullosaDog

64,90

Specific to the Golden Retriever and Central Asian Shepherd

Tests turnaround : 3-6 days or Express 3 days
Breeds : Berger d’Asie Centrale, Golden Retriever
Samples : Buccal swab, or Blood in EDTA tube, or Blood in dry tube

Clear
SKU: deb-dystrophic-epidermolysis-bullosa-dog Category:
N/N : Normal, no copies of the DEB mutation. N/DEB : Normal, one copy of the DEB mutation. DEB/DEB : 2 copies of the DEB mutation, the dog may develop this disease.

What is the DEB Dystrophic Epidermolysis Bullosa ?

The DEB is a disease that affects the skin of the Golden Retriever and the Central Asian Shepherd Dog. This disease is non-inflammatory. It forms lesions on the skin that contain fluids. The first symptoms of DEB appear just after the puppy birth. The symptoms are ulcers and small vesicles on the oral mucosa, on the back, on the nose, on the abdomen, on the genital parts and on the feet.

Type of sample

Here is the list of the different types of samples that are accepted for this test :
  • Buccal swab
  • Blood in EDTA tube
  • Blood in dry tube

Available breeds for the test : DEB Dystrophic Epidermolysis Bullosa - Dog


The following breeds are recognized :
  • Berger d'Asie Centrale
  • Golden Retriever

Understanding results of the test : DEB Dystrophic Epidermolysis Bullosa - Dog


N/N : Normal, no copies of the DEB mutation. N/DEB : Normal, one copy of the DEB mutation. DEB/DEB : 2 copies of the DEB mutation, the dog may develop this disease.
Test name : DEB Dystrophic Epidermolysis Bullosa - Dog
Gene Mutation : COL7A1
Heredity : autosomal recessive (more information)
Test resultDEB Dystrophic Epidermolysis Bullosa - Dog status (COL7A1 )Health status
N/NNo copy of the DEB mutationAnimal is normal (clear)
N/DEB1 copy of the DEB mutationAnimal is normal (clear)
DEB/DEB2 copies of the DEB mutationAnimal is, will or could be affected

Cross table of the test : DEB Dystrophic Epidermolysis Bullosa - Dog


Mother N/NMother N/DEBMother DEB/DEB
Father N/N100% N/N50% N/N
50% N/DEB
100% N/DEB
Father N/DEB50% N/N
50% N/DEB
25% N/N
50% N/DEB
25% DEB/DEB
50% N/DEB
50% DEB/DEB
Father DEB/DEB100% N/DEB50% N/DEB
50% DEB/DEB
100% DEB/DEB

Certificate example for the test : DEB Dystrophic Epidermolysis Bullosa - Dog

Click on the example certificate below to open it.

certificate

References

Baldeschi C, Gache Y, Rattenholl A, Bouillé P, Danos O, Ortonne JP, Bruckner-Tuderman L, Meneguzzi G. Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors. Hum Mol Genet. 2003 Aug 1;12(15):1897-905.

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