What is the HC Hereditary Cataract ?
The HC genetic disease affects about 8% of dogs in terrier breeds. This genetic disease was discovered in the late 1970s. The first signs of hereditary cataracts appear from a few weeks to a few months then the dog becomes completely blind after one or two years.
Available breeds for the test : HC Hereditary Cataract of Terrier
The following breeds are recognized :
- American Staffordshire Terrier
- Autre Race
- Bouledogue Français
- Staffordshire Bull Terrier
- Terrier De Boston
Understanding pụta nke ule: HC Hereditary Cataract of Terrier
Gene mutation: HSF4 g.85286582_insC
si n'aka ruo n'aka: autosomal recessive (ozi ọzọ)
|Test N'ihi||HC Hereditary Cataract of Terrier ọnọdụ (HSF4 g.85286582_insC)||Health status|
|N/N||No copy of the HC mutation||Animal is normal (clear)|
|N/HC||1 copy of the HC mutation||Animal is normal (clear)|
|HC/HC||2 copies of the HC mutation||Animal is, will or could be affected|
Cross table nke ule: HC Hereditary Cataract of Terrier
|nne N/N||nne N/HC||nne HC/HC|
|Nna N/N||100% N/N||50% N/N|
|Nna N/HC||50% N/N|
|Nna HC/HC||100% N/HC||50% N/HC|
Certificate atụ maka ule: HC Hereditary Cataract of Terrier
Pịa na atụ akwụkwọ n'okpuru imeghe ya.
Mellersh CS, Pettitt L, Forman OP, Vaudin M, Barnett KC. 2006. Identification of mutations in HSF4 in dogs of three different breeds with hereditary cataracts. Vet Ophthalmol. 9:369-378.
Mellersh CS, Graves KT, McLaughlin B, Ennis RB, Pettitt L, Vaudin M, Barnett KC. Mutation in HSF4 associated with early but not late-onset hereditary cataract in the Boston terrier. Journal of Heredity 2007; 98(5):531-533