What is the HYM Hypomyelination ?
The HYM is a disease found in Weimaraner dog. This neurological disease causes a delay in the response time of the myelin. The symptoms of the disease appear at the age of 2 weeks. The intensity of the symptoms varies according to the puppies. The puppies show tremors specifically in hind legs. The tremor episodes are more common during periods of exercise, of excitement, or during maternal breast feeding.
Type of sample
- Buccal swab
- Blood in EDTA tube
- Blood in dry tube
Razez disponibbli għat-test: HYM Hypomyelination - Dog
Ir-razez li ġejjin huma rrikonoxxuti:
- Braque De Weimar A Poil Court
- Braque De Weimar A Poil Long
Understanding results of the test : HYM Hypomyelination - Dog
Gene Mutation : FNIP2 c.880delA
Heredity : autosomal recessive (more information)
|Test result||HYM Hypomyelination - Dog status (FNIP2 c.880delA)||Health status|
|N/N||No copy of the HYM mutation||Animal is normal (clear)|
|N/HYM||1 copy of the HYM mutation||Animal is normal (clear)|
|HYM/HYM||2 copies of the HYM mutation||Animal is, will or could be affected|
Cross table of the test : HYM Hypomyelination - Dog
|Mother N/N||Mother N/HYM||Mother HYM/HYM|
|Father N/N||100% N/N||50% N/N|
|Father N/HYM||50% N/N|
|Father HYM/HYM||100% N/HYM||50% N/HYM|
Eżempju taċ-ċertifikat għat-test: HYM Hypomyelination - Dog
Ikklikkja fuq iċ-ċertifikat tal-e żempju hawn taħt biex tiftaħha.
Pemberton, Trevor J et al. “A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination” Glia vol. 62,1 (2014): 39-51.