PRA-b – Bengal Progressive Retinal Atrophy symptoms
The symptoms of PRA begin to occur in the kitten at the age of 2 months. Generally, the majority of cats become blind at 2 years old. The first signs are a difficulty to move in the dark.
New PRA-b DNA test
Initially, a test had been developed on a first genetic variant. The analysis of many Bengal cat has revealed another mutation that, to date, seems perfectly linked to the PRA-b. This new mutation is tested.
Available breed for the test : PRA-b - Bengal Progressive Retinal Atrophy
The following breed is recognized :
Understanding results of the test : PRA-b - Bengal Progressive Retinal Atrophy
Heredity : autosomal recessive (more information)
|Test result||PRA-b - Bengal Progressive Retinal Atrophy status ( )||Health status|
|N/N||No copy of the PRA-b mutation||Animal is normal (clear)|
|N/PRA-b||1 copy of the PRA-b mutation||Animal is normal (clear)|
|PRA-b/PRA-b||2 copies of the PRA-b mutation||Animal is, will or could be affected|
Cross table of the test : PRA-b - Bengal Progressive Retinal Atrophy
|Mother N/N||Mother N/PRA-b||Mother PRA-b/PRA-b|
|Father N/N||100% N/N||50% N/N|
|Father N/PRA-b||50% N/N|
|Father PRA-b/PRA-b||100% N/PRA-b||50% N/PRA-b|
Certificate example for the test : PRA-b - Bengal Progressive Retinal Atrophy
Click on the example certificate below to open it.
Ofri R, Reilly CM, Maggs DJ, Fitzgerald PG, Shilo-Benjamini Y, Good KL, Grahn
RA, Splawski DD, Lyons LA. Characterization of an early-onset, autosomal recessive, progressive retinal degeneration in Bengal cats. (2015) Investigative Ophthalmology & Visual Science Aug;56(9):5299-308. doi: 10.1167/iovs.15-16585. PubMed PMID: 26258614;PubMed Central PMCID: PMC4539567.