PRA pdProgressive Retinal Atrophy Persian

44,90

Specific to Persian, Exotic shorthair, Himalayan

Liliu e ngaahi sivi : 'aho 'e 3-6 pe fakaha ha 'aho 'e 3
Fakatupu ai ha : Exotic Shorthair, Persan
Sipinga : Buccal swab, pe ko e toto 'i EDTA tiupi, pe ko e toto 'i he tiupi momoa

Mahino
SKU pra-pd-progressive-retinal-atrophy-persian Fa'ahinga
N/N : Normal, no copy of the PRA-pd mutation. N/PRA-pd : Normal, one copy of the PRA-pd mutation. PRA-pd/PRA-pd : 2 copies of the PRA-pd mutation, the cat may develop this disease.

What is PRA pdProgressive Retinal Atrophy Persian?

The disease declared at 5 weeks old with blindness at 4 monthes.

Symptoms starts with eye movements that are not well coordinate.

Cats that are carriers (N/PRA-pd) have a normal vision even if we can observed changes in retinal pigment epithelium.

Fa'ahinga sipinga

Ko e lisi 'eni 'o e ngaahi sipinga kehekehe 'oku tali ki he sivi ko 'eni:
  • Buccal swab
  • Ko e toto 'i EDTA fo'i tiupi
  • Ko e toto 'i he tiupi momoa

'Oku ma'u ha fakatupu ki he sivi: PRA pd - Progressive Retinal Atrophy Persian


'Oku 'ilo'i 'a e ngaahi me'a ko 'eni:
  • Exotic Shorthair
  • Persan

Ngaahi ola 'o e sivi: PRA pd - Progressive Retinal Atrophy Persian


N/N : Normal, no copy of the PRA-pd mutation. N/PRA-pd : Normal, one copy of the PRA-pd mutation. PRA-pd/PRA-pd : 2 copies of the PRA-pd mutation, the cat may develop this disease.
Hingoa 'o e sivi: PRA pd - Progressive Retinal Atrophy Persian
Sini Mutation: AIPL1 c.577C>T
Ha taha autosomal recessive (fakamatala lahi ange)
Penetrance : complete (fakamatala lahi ange)
Ola 'o e siviPRA pd - Progressive Retinal Atrophy Persian tu'ungaAIPL1 c.577C>T)Tu'unga mo'ui lelei
N/NNo copy of the PRA pd mutation'Oku angamaheni pe 'a e monumanu (mahino)
N/PRA pd1 copy of the PRA pd mutation'Oku angamaheni pe 'a e monumanu (mahino)
PRA pd/PRA pd2 copies of the PRA pd mutationKo e fanga monumanu, 'e lava pe ke uesia

Tepile kolosi 'i he sivi: PRA pd - Progressive Retinal Atrophy Persian


Fa'ee N/NFa'ee N/PRA pdFa'ee PRA pd/PRA pd
Tamai N/N100% N/N50% N/N
50% N/PRA pd
100% N/PRA pd
Tamai N/PRA pd50% N/N
50% N/PRA pd
25% N/N
50% N/PRA pd
25% PRA pd/PRA pd
50% N/PRA pd
50% PRA pd/PRA pd
Tamai PRA pd/PRA pd100% N/PRA pd50% N/PRA pd
50% PRA pd/PRA pd
100% PRA pd/PRA pd

Sipinga 'o e tohi fakamo'oni ki he sivi: PRA pd - Progressive Retinal Atrophy Persian

Lomi'i 'i he sipinga 'o e tohi fakamo'oni 'i lalo ke fakaava.

Tohi fakamo'oni

Ngaahi potufolofola

Rah H, Maggs DJ, Blankenship TN, Narfstom K, Lyons LA. 2005. Early-Onset, Autosomal Recessive, Progressive Retinal Atrophy in Persian Cats. Invest. Ophthalmol. Vis. Sci. 46:1742-1747.

Vakai'i

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