PRA rdyProgressive Retinal Atrophy

44,90

Specific to Abyssin, Somali breeds

Ukuhlolwa sokwenza : 3-6 izinsuku noma Express 3 izinsuku
Kuzala : Abyssin, Somali
amasampula : Buccal swab, noma igazi EDTA tube, noma igazi tube ezomile

Sula
SKU: pra-rdy-progressive-retinal-atrophy-abyssin-somali Isigaba:
N/N : Normal, no copy of the PRA rdy mutation. N/PRA rdy : one copy of the PRA rdy mutation, the cat may develop this disease. PRA rdy/PRA rdy : 2 copies of the PRA rdy mutation, the cat may develop this disease.

What is PRA rdyProgressive Retinal Atrophy?

PRA rdyProgressive Retinal Atrophy is a specific mutation found in Abyssin and Somali cat. This disease produce rod cone dysplasia. Kittens will be blind at around 7 weeks old due to a defective protein which is needed for the normal eye development.

Ukuqonda imiphumela yokuhlola: PRA rdy - Progressive Retinal Atrophy


N/N : Normal, no copy of the PRA rdy mutation. N/PRA rdy : one copy of the PRA rdy mutation, the cat may develop this disease. PRA rdy/PRA rdy : 2 copies of the PRA rdy mutation, the cat may develop this disease.
igama Test: PRA rdy - Progressive Retinal Atrophy
Gene Kwezakhi: CRX n.546delC
ufuzo: autosomal evelele (ukwaziswa okwengeziwe)
Penetrance : complete (ukwaziswa okwengeziwe)
yi TestPRA rdy - Progressive Retinal Atrophy isimo (CRX n.546delC)isimo Impilo
N/NNo copy of the PRA rdy mutationAnimal kuyinto evamile (ecacile)
PRA rdy/N1 copy of the PRA rdy mutationAnimal amazwi, ingabe noma kungathonyeka
PRA rdy/PRA rdy2 copies of the PRA rdy mutationAnimal amazwi, ingabe noma kungathonyeka

ithebula Cross test: PRA rdy - Progressive Retinal Atrophy


umama N/Numama PRA rdy/Numama PRA rdy/PRA rdy
ubaba N/N100% N/N50% N/N
50% PRA rdy/N
100% PRA rdy/N
ubaba PRA rdy/N50% N/N
50% PRA rdy/N
25% N/N
50% PRA rdy/N
25% PRA rdy/PRA rdy
50% PRA rdy/N
50% PRA rdy/PRA rdy
ubaba PRA rdy/PRA rdy100% PRA rdy/N50% PRA rdy/N
50% PRA rdy/PRA rdy
100% PRA rdy/PRA rdy

Isitifiketi isibonelo isivivinyo: PRA rdy - Progressive Retinal Atrophy

Chofoza isitifiketi isibonelo ngezansi ukuze uyivule.

isitifiketi

Izinkomba

Menotti-Raymond M, Deckman KH, David V, Myrkalo J, O’Brien SJ, Narfström K. Mutation discovered in a feline model of human congenital retinal blinding disease. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):2852-9. Epub 2010 Jan 6. PubMed PMID: 20053974.

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